Aplication Discussion ADHD

Application Discussion (ADHD)
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Application Discussion (ADHD)
Attention-deficit/hyperactivity disorder (ADHD) is a neuro-developmental disorder associated with symptoms such as hyperactivity, impulsivity, and inattention. About 5% of the children worldwide suffer from ADHD which is the most prevalent mental health problems in children (Thomas, Sanders, Doust, Beller, & Glasziou, 2015). ADHD was once a western condition encouraged by the western cultures. However, the current study shows that ADHD is a compound, multi-factorial disorder with numerous living etiologies, such as genetics (Lecendreux, Lavault, Lopez, Inocente, Konofal, Cortese, & Dauvilliers, 2015). In this case, I focus my study on the human dopamine receptor DRD4 gene. The gene is located near the telomere of chromosome 11p where the amount of expressed polymorphism is exhibited. DRD4 contains a 48-bp Variable Number Tandem Repeat (VNTR) polymorphism in exon 3 consisting of a 48-base-pair repeat unit with 2R, 4R, and 7R repeats as the common versions.
According to studies, the 7R allele encodes a receptor with lower similarity for dopamine (Hockley, 2017). It is linked with diverse psychiatric disorders including ADHD. Genes like DRD4 has received more attention in many disorders compared to other genotypes, describing it in connection with precise behavioral problems such as personality trait of novelty seeking, short temper, anger, and aggressive behavior. DR…